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Keywords: threshold effect
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Biochem J (2003) 370 (3): 751–762.
Published: 15 March 2003
... diseases. The results have shown that, in most cases, phenotypic manifestation of the genetic defect occurs only when a threshold level is exceeded, and this phenomenon has been named the ‘phenotypic threshold effect'. Subsequently, several authors showed that it was possible to inhibit considerably...
Biochem J (2001) 357 (3): 835–842.
Published: 25 July 2001
... in the expression of mitochondrial DNA mutations and thus the importance of the origin of the deficit (mutation) for the diagnosis or therapy of mitochondrial diseases. Key words: metabolic control analysis, oxidative phosphoryl- ation, threshold effect. the activity of this complex with a homogeneous distribution...