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1-8 of 8
Keywords: thyroid hormone
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Articles
Thyroid hormones regulate phosphate homoeostasis through transcriptional control of the renal type IIa sodium-dependent phosphate co-transporter ( Npt2a ) gene
Available to PurchaseMariko Ishiguro, Hironori Yamamoto, Masashi Masuda, Mina Kozai, Yuichiro Takei, Sarasa Tanaka, Tadatoshi Sato, Hiroko Segawa, Yutaka Taketani, Hidekazu Arai, Ken-ichi Miyamoto, Eiji Takeda
Journal:
Biochemical Journal
Biochem J (2010) 427 (1): 161–169.
Published: 15 March 2010
... of serum phosphate levels. It has been demonstrated previously that renal Npt2a protein and its mRNA expression are both up-regulated by the thyroid hormone T 3 (3,3′,5-tri-iodothyronine) in rats. However, it has never been established whether the induction was mediated by a direct effect of thyroid...
Includes: Supplementary data
Articles
Regulation and function of selenoproteins in human disease
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2009) 422 (1): 11–22.
Published: 29 July 2009
... neurodegeneration selenium selenocysteine selenoprotein thyroid hormone The trace element selenium (Se), originally viewed as a toxin, is now understood to be an important micronutrient [ 1 ]. Selenium is incorporated into proteins not simply though ionic association, as most metals...
Includes: Multimedia, Supplementary data
Articles
In vitro selection and characterization of RNA aptamers binding thyroxine hormone
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2007) 403 (1): 129–138.
Published: 13 March 2007
... (3000 Ci/mmol) and T4 RNA ligase as described by the manufacturer (New England Biolabs), and then purified as described above. aptamer riboswitch RNA ligand thyroid hormone thyroxine (T4) tri-iodothyronine (T3) Several of the original discoveries of biological molecules binding RNA...
Articles
Thyroid hormones directly activate the expression of the human and mouse uncoupling protein-3 genes through a thyroid response element in the proximal promoter region
Available to PurchaseGemma SOLANES, Neus PEDRAZA, Verónica CALVO, Antonio VIDAL-PUIG, Bradford B. LOWELL, Francesc VILLARROYA
Journal:
Biochemical Journal
Biochem J (2005) 386 (3): 505–513.
Published: 08 March 2005
... status also modulate UCP3 gene expression, albeit by unknown mechanisms. We created transgenic mice bearing the entire human UCP3 gene to investigate the effect of thyroid hormones on human UCP3 gene expression. Treatment of human UCP3 transgenic mice with thyroid hormones induced the expression...
Articles
Thyroid-hormone-dependent negative regulation of thyrotropin beta gene by thyroid hormone receptors: study with a new experimental system using CV1 cells
Available to PurchaseKeiko NAKANO, Akio MATSUSHITA, Shigekazu SASAKI, Hiroko MISAWA, Kozo NISHIYAMA, Yumiko KASHIWABARA, Hirotoshi NAKAMURA
Journal:
Biochemical Journal
Biochem J (2004) 378 (2): 549–557.
Published: 01 March 2004
...Keiko NAKANO; Akio MATSUSHITA; Shigekazu SASAKI; Hiroko MISAWA; Kozo NISHIYAMA; Yumiko KASHIWABARA; Hirotoshi NAKAMURA The molecular mechanism involved in the liganded thyroid hormone receptor suppression of the TSHβ (thyroid-stimulating hormone β, or thyrotropin β) gene transcription...
Articles
Hormonal regulation of the human sterol 27-hydroxylase gene CYP27A1
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2003) 372 (2): 529–534.
Published: 01 June 2003
... (IGF-1), dexamethasone, thyroid hormones and PMA was studied. HepG2 cells were transfected transiently with luciferase reporter gene constructs containing DNA fragments flanking the 5′-region of the human CYP27A1 gene. GH, IGF-1 and dexamethasone increased the promoter activity by 2–3-fold, whereas...
Articles
Novel human ZAKI-4 isoforms: hormonal and tissue-specific regulation and function as calcineurin inhibitors
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2002) 367 (2): 459–466.
Published: 15 October 2002
...Xia CAO; Fukushi KAMBE; Takashi MIYAZAKI; Devanand SARKAR; Sachiko OHMORI; Hisao SEO We identified a thyroid hormone [3,5,3′-tri-iodothyronine (T 3 )]-responsive gene, ZAKI-4, in cultured human skin fibroblasts. It belongs to a family of genes that encode proteins containing a conserved motif...
Articles
Thyroxine regulation of monolysocardiolipin acyltransferase activity in rat heart
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2000) 346 (2): 403–406.
Published: 22 February 2000
...-fold ( P < 0.025) increase in mitochondrial monolysocardiolipin acyltransferase activity. The results demonstrate that the acylation of cardiac monolysocardiolipin is regulated by thyroid hormone. Thus an elevation in cardiolipin biosynthesis is accompanied by an elevation in monolysocardiolipin...