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1-7 of 7
Keywords: tissue inhibitor of metalloproteinase (TIMP)
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Articles
Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2)
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2010) 430 (1): 79–86.
Published: 28 July 2010
... Society 2010 1 M. K. and J. J. contributed equally to this study. 2 U. W. and G. M. contributed equally to this study. a disintegrin and metalloprotease 12 (ADAM12) ectodomain shedding therapeutic target tissue inhibitor of metalloproteinase (TIMP) tumour necrosis factor α...
Articles
The isolated N-terminal domains of TIMP-1 and TIMP-3 are insufficient for ADAM10 inhibition
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2008) 411 (2): 433–439.
Published: 27 March 2008
... Society 2008 ADAM10 CD44 inhibition shedding tissue inhibitor of metalloproteinase (TIMP) tumour necrosis factor α converting enzyme (TACE) The ADAM (a disintegrin and metalloproteinase) family consists of modular type I transmembrane proteins that contain a metalloproteinase...
Articles
Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells: (auto-)catalytic activation and resistance to inhibition by TIMP-1
Available to PurchaseChristian Ries, Thomas Pitsch, Reinhard Mentele, Stefan Zahler, Virginia Egea, Hideaki Nagase, Marianne Jochum
Journal:
Biochemical Journal
Biochem J (2007) 405 (3): 547–558.
Published: 13 July 2007
...) were used. The developed films were scanned and analysed using the ImageMaster-1D Elite software. acute myeloid leukaemia gelatinase B glycosylation matrix metalloproteinase (MMP) tissue inhibitor of metalloproteinase (TIMP) tumour cell invasion MMPs (matrix metalloproteinases...
Articles
TIMP-3 inhibits the procollagen N-proteinase ADAMTS-2
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Journal:
Biochemical Journal
Biochem J (2006) 398 (3): 515–519.
Published: 29 August 2006
...) extracellular matrix metalloproteinase procollagen tissue inhibitor of metalloproteinase (TIMP) The major fibrillar collagens, which constitute the major fibrous components of vertebrate ECM (extracellular matrix), are synthesized as procollagens, with N- and C-propeptides that must be cleaved...
Articles
Cleavage at the stem region releases an active ectodomain of the membrane type 1 matrix metalloproteinase
Available to PurchaseMarta TOTH, Pamela OSENKOWSKI, Dusan HESEK, Stephen BROWN, Samy MEROUEH, Wael SAKR, Shahriar MOBASHERY, Rafael FRIDMAN
Journal:
Biochemical Journal
Biochem J (2005) 387 (2): 497–506.
Published: 05 April 2005
... metalloproteinase (MMP) shedding protease proteolysis tissue inhibitor of metalloproteinase (TIMP) MT1-MMP (membrane type 1 matrix metalloproteinase) is a type I membrane-anchored MMP that has been shown to play a critical role in the pericellular degradation of connective tissue matrix by directly...
Includes: Supplementary data
Articles
The ADAMTS metalloproteinases
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2005) 386 (1): 15–27.
Published: 08 February 2005
... (email [email protected] ). 15 3 2004 18 11 2004 19 11 2004 19 11 2004 The Biochemical Society, London 2005 aggrecanase angiogenesis extracellular matrix metalloproteinase proteoglycan tissue inhibitor of metalloproteinase (TIMP) Kuno et al. [ 1...
Articles
Identification of an initiator-like element essential for the expression of the tissue inhibitor of metalloproteinases-4 (Timp-4) gene
Available to PurchaseDavid A. YOUNG, Blaine W. PHILLIPS, Caroline LUNDY, Robert K. NUTTALL, Aileen HOGAN, Gilbert A. SCHULTZ, Kevin J. LECO, Ian M. CLARK, Dylan R. EDWARDS
Journal:
Biochemical Journal
Biochem J (2002) 364 (1): 89–99.
Published: 08 May 2002
... These authors contributed equally to this work. 2 To whom correspondence should be addressed (e-mail [email protected] ). 12 11 2001 24 1 2002 6 3 2002 The Biochemical Society, London ©2002 2002 promoter quantitative RT-PCR tissue inhibitor of metalloproteinase (TIMP...