... positioned and Fis compensates for this impediment by facilitating RNA polymerase recruitment. bacterial multi-subunit RNA polymerase bacterial promoters enteroaggregative E. coli (EAEC) Shigella sonnei transcription initiation uropathogenic E. coli (UPEC) Autotransporters...

...Hsin-Yi Yeh; Hsiu-Ting Hsu; Tsung-Ching Chen; Kuei-Min Chung; Kung-Ming Liou; Ban-Yang Chang Sigma (σ) factors are bacterial transcription initiation factors that direct transcription at cognate promoters. The promoters recognized by primary σ are composed of −10 and −35 consensus elements...

... conformations, thereby affecting transcription initiation/activation. We argue that Mediator is formed by highly disordered proteins with large densely packed interfaces that make efficient long-range signal propagation possible. We suggest two possible general mechanisms for Mediator action: one in which...

... can drive transcript initiation 10 bp upstream of the P1 promoter transcript start point. Because of the overlap between P1 and P1A, P1A activity is unmasked only when the P1 promoter is inactivated by mutation. In the present paper, we report that mutation of the P1–10 element is less effective...