... exchange in transcriptional functions of nuclear receptors Genes Dev. 2000 14 121 141 10652267 18 Mazumdar A. Wang R.A. Mishra S.K. Adam L. Bagheri-Yarmand R. Mandal M. Vadlamudi R.K. Kumar R. Transcriptional repression of oestrogen receptor by metastasis...

... not yet been elucidated. dominant negative hepatocyte nuclear receptor transcriptional repression Cyp7a1 (cytochrome P450, family 7, subfamily a, polypeptide 1; also known as cholesterol 7α-hydroxylase) catalyses the first and rate-limiting step in the catabolism of cholesterol to bile...

... and reproduction in any medium, provided the original work is properly cited. chromatin epigenetics FAD-dependent oxidase histone modification transcriptional repression The term ‘epigenetic’ refers to heritable changes regulating gene expression that are not a result of changes...

... in the transcriptional activity assays. Oligonucleotide sequences are given in the Supplementary Table S1 (at http://www.BiochemJ.org/bj/438/bj4380437add.htm ). Drosophila histone deacetylase (HDAC) small ubiquitin-related modifier (SUMO) Spalt-like (SALL) transcriptional repression SALL (Spalt...

... have shown previously that PRH is a repressor of transcription in haematopoietic cells and that an Eh-1 (Engrailed homology) motif present within the N-terminal transcription repression domain of PRH mediates binding to Groucho/TLE proteins and enables co-repression. In the present study we demonstrate...

... 2006 The Biochemical Society, London 2007 CCAAT/enhancer-binding protein α (C/EBPα) phosphoenolpyruvate carboxykinase (PEPCK) protein–protein interactions short heterodimer partner (SHP) transcriptional repression PEPCK (phosphoenolpyruvate carboxykinase) is an enzyme...

... ). 12 6 2006 23 6 2006 27 6 2006 27 6 2006 The Biochemical Society, London 2006 Brahma-related gene 1 (Brg1) co-repressor erythroid progenitor histone deacetylase SWI/SNF transcriptional repression Development is a highly regulated process involving the ordered...

... using different p21Cip1 promoter mutants showed that transcriptional repression of p21Cip1 by c-Myc was mediated through Miz-1- and Sp1-binding sites within the proximal region of the p21Cip1 promoter in normal IECs. These findings confirm that p21Cip1 is one of the direct mediators of induced c-Myc...

... receptor (AR) mutation nuclear receptor co-repressor (N-CoR) transcriptional intermediary factor 2 (TIF2) transcriptional repression Abbreviations used: AD, activation domain; AR, androgen receptor; BIC, bicalutamide; CHO, Chinese-hamster ovary; CPA, cyproterone acetate; DHT...

... , and the proteolytic activity of the proteasome is not required for transcriptional repression by PRH. However, proteasomal digestion of PRH can liberate truncated PRH proteins that retain the ability to bind to DNA. We discuss these findings in terms of the biological role of PRH in gene regulation and the control...

... action(s) of CTIPs in cells that do not express COUP-TF family members, such as cells of the haematopoietic and immune systems. Key words: Bcl11b, Evi9}Bcl11a, leukaemia, oligomerization, transcriptional repression. scription factor (COUP-TF)-interacting proteins 1 and 2 [CTIP1}Evi9}B cell leukaemia (Bcl...

... 2002 The Biochemical Society, London ©2002 2002 cAMP SMRT transcriptional repression Abbreviations used: PPAR, peroxisome-proliferator-activated receptor; RXR, retinoid X receptor; RAR, retinoic acid receptor; TR, thyroid hormone receptor; HLBD, hinge and ligand-binding domain...

... related to invertebrate and vertebrate transcriptional repressors of the Groucho/transducin-like Enhancer of split (TLE) family. The aim was to examine whether similar mechanisms underlie the transcription repression functions of TUP1 and Groucho/TLEs by determining whether TLE family members can interact...