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Keywords: translocator protein (TSPO)
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Articles

The mitochondrial translocator protein (TSPO): a key multifunctional molecule in the nervous system

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Léa El Chemali, Yvette Akwa, Liliane Massaad-Massade
Journal: Biochemical Journal
Biochem J (2022) 479 (13): 1455–1466.
https://doi.org/10.1042/BCJ20220050
Published: 12 July 2022
...Léa El Chemali; Yvette Akwa; Liliane Massaad-Massade Translocator protein (TSPO, 18 kDa), formerly known as peripheral benzodiazepine receptor, is an evolutionary well-conserved protein located on the outer mitochondrial membrane. TSPO is involved in a variety of fundamental physiological functions...
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Articles

TSPO: kaleidoscopic 18-kDa amid biochemical pharmacology, control and targeting of mitochondria

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Jemma Gatliff, Michelangelo Campanella
Journal: Biochemical Journal
Biochem J (2016) 473 (2): 107–121.
https://doi.org/10.1042/BJ20150899
Published: 05 January 2016
...Jemma Gatliff; Michelangelo Campanella The 18-kDa translocator protein (TSPO) localizes in the outer mitochondrial membrane (OMM) of cells and is readily up-regulated under various pathological conditions such as cancer, inflammation, mechanical lesions and neurological diseases. Able to bind...
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