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Keywords: translocon
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Articles
Biochem J (2021) 478 (22): 4005–4024.
Published: 23 November 2021
... complex. Mycolactone has previously been shown to bind to, and alter the structure of the major translocon subunit Sec61α, and change its interaction with ribosome nascent chain complexes. In addition to its function in protein translocation into the ER, Sec61 also plays a key role in cellular Ca 2...
Includes: Supplementary data
Articles
Biochem J (2011) 436 (2): 291–303.
Published: 13 May 2011
... of Sss1p were tolerated, but deletion of the 12 residues C-terminal of the hydrophobic sequence disrupted the translocation function of the Sec61 complex [ 30 ]. The molecular cause of the functional defect in translocons with large deletions in Sss1p remains unclear because the mutant Sss1p proteins still...
Includes: Supplementary data
Articles
Biochem J (2010) 426 (2): 135–145.
Published: 09 February 2010
... peptides. h-Regions are ‘scaffolds’ in which functional h-motifs are embedded. A hypothetical model for h-motif interactions with a Sec61p protein translocon is presented. 1 These authors contributed equally to this work. 2 Present address: Department of Medical Education, Paul L. Foster...
Includes: Supplementary data
Articles
Biochem J (2008) 413 (1): 15–28.
Published: 12 June 2008
... in Arabidopsis thaliana ) after completion of their synthesis on cytoplasmic ribosomes [ 5 , 6 ]. 4 3 2008 1 5 2008 2 5 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 chaperone chloroplast plastid protein import protein targeting translocon Although...
Articles
Biochem J (2005) 390 (2): 455–464.
Published: 23 August 2005
... to decreased transcription or translation levels. Thus the signal peptide of the CRF-R1 promotes an early step of receptor biogenesis, such as targeting of the nascent chain to the ER membrane and/or the gating of the protein-conducting translocon of the ER membrane. 1 To whom correspondence should...
Articles
Biochem J (2003) 370 (1): 351–355.
Published: 15 February 2003
...-translational process that precedes GPI anchor addition and, as such, will be greatly influenced by the dynamics of the translocon—oligosaccharyltransferase complex. 1 To whom correspondence should be addressed (e-mail n.m.hooper@leeds.ac.uk ). 19 8 2002 29 11 2002 2 12 2002 2 12...