... M. Buck Transmembrane proteins have unique requirements to fold and integrate into the endoplasmic reticulum (ER) membrane. Most notably, transmembrane proteins must fold in three separate environments: extracellular domains fold in the oxidizing environment of the ER lumen, transmembrane domains...

[email protected] ) 19 6 2022 30 9 2022 17 10 2022 © 2022 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2022 endocytosis Kaposi's sarcoma-associated herpesvirus molecular interactions transmembrane proteins ubiquitin ligases...

... light harvesting photosynthesis reaction centre transmembrane proteins Superposition of the monomeric RC-LH1 structure [ 10 ] onto one half of the dimer (not shown) indicates an almost exact correspondence (RMSD of 0.177 Å) between the structures. Thus, all of the structural and functional...

... on behalf of the Biochemical Society 2019 endoplasmic reticulum three-way junctions transmembrane proteins The U2OS cells transfected with the TMCC3 siRNAs or the control siRNA were fixed with 4% paraformaldehyde and permeabilized with 0.2% Triton X-100, followed by immunostaining...

... Attribution License 4.0 (CC BY-NC-ND) . cholesterol high-density lipoprotein proline scavenger receptors SR-BI transmembrane proteins Approximately one in three deaths (30.8%) in the U.S.A. are cardiovascular disease-related [ 1 ]. Most cardiovascular disease events result from...

... Limited on behalf of the Biochemical Society 2019 lipid transfer phosphatidylinositol phosphoinositide 3-kinase PTEN transmembrane proteins PPIs (polyphosphoinositides) are reversibly phosphorylated derivatives of the membrane phospholipid phosphatidylinositol (PI, Figure 1A...

...). Published by Portland Press Limited on behalf of the Biochemical Society 2018 cholesterol lipid rafts pore-forming toxins transmembrane proteins Vibrio cholerae cytolysin Vibrio cholerae is the etiologic agent of the disease cholera, a condition in humans characterized by voluminous...

... assignments. The identity of phospholipid peaks was verified using the LIPID MAPS: Nature Lipidomics Gateway ( www.lipidmaps.org ). glycosome Leishmania membrane proteins peroxin PEX14 transmembrane proteins Leishmania , like other medically important kinetoplastid parasites, have...

... Saccharomyces cerevisiae site-directed mutagenesis transmembrane proteins transport The protocol for in vitro random mutagenesis was adopted from Rose and Fink (1987) [ 22 ]. Briefly, 10 µg purified plasmid (p416TEF-His-HGT1-HA) was mixed in 0.5 ml freshly made hydroxylamine solution (350 mg...

... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . electron microscopy transmembrane proteins transport Figure 2. Electron micrographs of E. coli cells, overexpressing TatA, immunogold-labelled following primary antibody detection against...