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1-4 of 4
Keywords: transmissible spongiform encephalopathy
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Articles
Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin
Open AccessSabrina Cronier, Nathalie Gros, M. Howard Tattum, Graham S. Jackson, Anthony R. Clarke, John Collinge, Jonathan D. F. Wadsworth
Journal:
Biochemical Journal
Biochem J (2008) 416 (2): 297–305.
Published: 12 November 2008
... (PrP) scrapie thermolysin transmissible spongiform encephalopathy variant Creutzfeldt–Jakob disease (vCJD) Prion diseases are fatal neurodegenerative disorders that include CJD (Creutzfeldt–Jakob disease), GSS (Gerstmann–Sträussler–Scheinker disease), FFI (fatal familial insomnia), kuru...
Articles
Proteinase K-sensitive disease-associated ovine prion protein revealed by conformation-dependent immunoassay
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2007) 401 (2): 475–483.
Published: 21 December 2006
... proteinase K proteolysis transmissible spongiform encephalopathy Prion diseases, or TSEs (transmissible spongiform encephalopathies), are chronic neurodegenerative CNS (central nervous system) disorders of mammals. This group of invariably fatal conditions includes scrapie of sheep, BSE (bovine...
Articles
Conformational variation between allelic variants of cell-surface ovine prion protein
Available to PurchaseAlana M. THACKRAY, Sujeong YANG, Edmond WONG, Tim J. FITZMAURICE, Robert J. MORGAN-WARREN, Raymond BUJDOSO
Journal:
Biochemical Journal
Biochem J (2004) 381 (1): 221–229.
Published: 22 June 2004
... were verified by MS to confirm the correct protein sequence and the presence of a disulphide bond. epitope polymorphism PrP C ruminant secondary structure transmissible spongiform encephalopathy Prion diseases, such as scrapie in sheep, bovine spongiform encephalopathy in cattle...
Articles
Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant
Available to PurchaseSheena M. WHYTE, Ian D. SYLVESTER, Stephen R. MARTIN, Andrew C. GILL, Franziska WOPFNER, Hermann M. SCHÄTZL, Guy G. DODSON, Peter M. BAYLEY
Journal:
Biochemical Journal
Biochem J (2003) 373 (2): 485–494.
Published: 15 July 2003
... progression. Genetic variation in PRND does not appear to influence the pathogenesis of prion diseases [17], the absence of Dpl does not affect scrapie pathogenesis in neural grafts [18], and expression of Dpl apparently has no influence on the outcome of transmissible spongiform encephalopathy disease...