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Keywords: tubulo-interstitial fibrosis
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Articles
The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFβ1 responses in human proximal-tubule epithelial cells
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Journal:
Biochemical Journal
Biochem J (2006) 393 (2): 601–607.
Published: 23 December 2005
...Mysore K. Phanish; Nadia A. Wahab; Paul Colville-Nash; Bruce M. Hendry; Mark E. C. Dockrell In chronic renal diseases, progressive loss of renal function correlates with advancing tubulo-interstitial fibrosis. TGFβ1-Smad (transforming growth factor-β1–Sma and Mad protein) signalling plays...