1-21 of 21
Keywords: tumour necrosis factor α (TNFα)
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Biochem J (2014) 459 (3): 479–488.
Published: 11 April 2014
... necrosis factor α (TNFα) Inflammation plays an important role in the development of peripheral insulin resistance in Type 2 diabetes [ 1 ]. Elevated levels of the pro-inflammatory cytokine TNFα (tumour necrosis factor α) are found in plasma [ 2 ], adipose tissue [ 3 ] and skeletal muscle [ 4 ] in...
Includes: Supplementary data
Articles
Biochem J (2013) 449 (1): 275–284.
Published: 07 December 2012
... (TfR1) tumour necrosis factor α (TNFα) NF-κB (nuclear factor κB) is the collective name of a family of transcription factors consisting of seven proteins, encoded by five genes: RelA, RelB, c-Rel, p105/p50 and p100/p52 [ 1 ]. All of these proteins are related via a highly conserved DNA-binding...
Includes: Supplementary data
Articles
Biochem J (2012) 443 (3): 857–867.
Published: 16 April 2012
.../2.5/ ) which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited. bioinformatics cytokine inflammation promoter PIK3CD tumour necrosis factor α (TNFα) PI3Ks (phosphoinositide 3-kinases) phosphorylate...
Includes: Supplementary data
Articles
Biochem J (2012) 442 (1): 127–137.
Published: 27 January 2012
... phospholipase A 2 (PLA2G4C) inflammation lung tumour necrosis factor α (TNFα) Whole lungs from mice were flash-frozen in liquid nitrogen and total RNA was isolated [ 18 ]. cDNA was produced and real-time RT–PCR was performed using an ABI 7000 Sequence Detection System. Briefly, 1 μg of total RNA was...
Includes: Supplementary data
Articles
Biochem J (2012) 441 (1): 339–346.
Published: 14 December 2011
... factor)-associated nuclear factor κB activator]-binding kinase 1 (TBK1) tumour necrosis factor α (TNFα) Toll-like receptor (TLR) Pellino was originally discovered in the Toll signalling pathway of Drosophila melanogaster as a protein that interacts with Pelle, the orthogue of IRAK {IL-1R [IL...
Includes: Supplementary data
Articles
Biochem J (2011) 435 (3): 755–769.
Published: 13 April 2011
... called MAPKAPK2) protein kinase A (PKA) tumour necrosis factor α (TNFα) Activated p38 MAPK exerts its cellular actions by phosphorylating, and thus activating, the predominant downstream kinase MK2 (MAPK-activated protein kinase 2, also called MAPKAPK2) and its compensatory kinase, MK3 (MAPKAPK3...
Articles
Biochem J (2011) 434 (2): 253–263.
Published: 11 February 2011
...@vetbio.uzh.ch ). 5 8 2010 5 11 2010 16 12 2010 16 12 2010 © The Authors Journal compilation © 2011 Biochemical Society 2011 cellular localization gene expression inhibitory κB β (IκBβ) nuclear factor κB (NF-κB) tumour necrosis factor α (TNFα) NF-κB (nuclear factor...
Includes: Supplementary data
Articles
Biochem J (2010) 427 (3): 435–443.
Published: 14 April 2010
... mitogen-activated protein kinase (MAPK) mixed lineage kinase 3 (MLK3) proteasome tumour necrosis factor α (TNFα) The activities and signalling pathways of many protein kinases are controlled through post-translational modifications. Reversible phosphorylation is the most common post...
Includes: Supplementary data
Articles
Biochem J (2010) 426 (3): 345–354.
Published: 24 February 2010
...) histone acetylation histone deacetylase 1 (HDAC1) nuclear factor κB (NF-κB) RelA (p65) tumour necrosis factor α (TNFα) Members of the NF-κB (nuclear factor κB) transcription factor family are known to regulate a variety of cellular processes including inflammatory and immune responses, cell...
Includes: Supplementary data
Articles
Biochem J (2010) 425 (1): 169–180.
Published: 14 December 2009
... should be addressed (email paramesw@msu.edu ). 18 6 2009 18 9 2009 2 10 2009 2 10 2009 © The Authors Journal compilation © 2010 Biochemical Society 2010 G-protein-coupled-receptor kinase (GRK) inflammation macrophage nuclear factor κB (NF-κB) tumour necrosis factor...
Includes: Supplementary data
Articles
Biochem J (2008) 410 (3): 575–583.
Published: 27 February 2008
... junction tumour necrosis factor α (TNFα) The reduction of CLMP mRNA levels upon TNFα treatment could be mediated through gene transcription and/or post-transcriptional modification. To examine whether TNFα alters CLMP mRNA levels via gene transcription, TM4 cells were transfected with the...
Articles
Biochem J (2008) 409 (3): 711–722.
Published: 15 January 2008
... factor β-activated protein kinase 1 (TAK1) tumour necrosis factor α (TNFα) The uncontrolled production of TNFα (tumour necrosis factor α) and other pro-inflammatory cytokines is a major cause of chronic inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease. TAK1...
Articles
Biochem J (2007) 408 (2): 277–286.
Published: 14 November 2007
... ). 15 2 2007 8 8 2007 10 8 2007 10 8 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 CCAAT/enhancer-binding protein (C/EBP) HL60 cell phospholipid hydroperoxide glutathione peroxidase (PHGPx) promoter activity tumour necrosis factor α (TNFα...
Articles
Biochem J (2007) 407 (2): 243–254.
Published: 25 September 2007
... (email sbhatta3@utmem.edu ). 28 2 2007 25 6 2007 9 7 2007 9 7 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 α-difluromethylornithine (DFMO) epithelium p130Cas polyamine Src tumour necrosis factor α (TNFα) Apoptosis in the intestinal...
Articles
Biochem J (2006) 398 (3): 439–450.
Published: 29 August 2006
...) co-activators hepatocyte nuclear factor 4 (HNF-4) nuclear factor κB (NF-κB) transcriptional inhibition tumour necrosis factor α (TNFα) HNF-4 (hepatocyte nuclear factor 4) belongs to the hormone nuclear receptor gene superfamily of transcription factors on the basis of its domain...
Articles
Biochem J (2006) 397 (1): 61–67.
Published: 14 June 2006
... ). 6 2 2006 24 3 2006 27 3 2006 27 3 2006 The Biochemical Society, London 2006 anaemia of chronic disease (ACD) ferritin hypoferraemia iron iron-regulated protein 1 (IREG1) tumour necrosis factor α (TNFα) ACD (anaemia of chronic disease) or anaemia of chronic...
Articles
Biochem J (2005) 392 (2): 325–334.
Published: 22 November 2005
...@wayne.edu ). 18 2 2005 20 5 2005 8 6 2005 8 6 2005 The Biochemical Society, London 2005 apoptosis cathepsin D lysosome NPe6 3- O -methylsphingomyelin photodynamic therapy procaspase tumour necrosis factor α (TNFα) The endosomal/lysosomal system consists of a...
Articles
Biochem J (2005) 391 (3): 575–580.
Published: 25 October 2005
... inflammation lipopolysaccharide macrophage tumour necrosis factor α (TNFα) Adenosine released from stressed cells can act as a physiological inhibitor of inflammation [ 1 ]. Utilization of ATP during periods of high metabolic activity leads to an increased concentration of intracellular adenosine...
Articles
Biochem J (2005) 391 (2): 399–408.
Published: 10 October 2005
... factor α (TNFα) GSH is the main non-protein thiol in mammalian cells that participates in many critical cellular functions including antioxidant defence and cell growth [ 1 – 3 ]. GSH is synthesized in the cytosol of all mammalian cells via two ATP-requiring enzymatic steps: the formation of γ...
Articles
Biochem J (2005) 390 (1): 317–324.
Published: 09 August 2005
... cytokine endothelial cell microvascular nuclear factor-κB1 (NF-κB1) RelA homodimer tumour necrosis factor α (TNFα) In a variety of cell types, cytokines regulate the expression of many viral and cellular genes through the transcriptional factor NF-κB (nuclear factor κB) (reviewed in [ 1 – 3...
Articles
Biochem J (2005) 386 (3): 445–451.
Published: 08 March 2005
... translocation ceramide mitochondrion sphingomyelinase tumour necrosis factor α (TNFα) Apoptosis induced by TNFα (tumour necrosis factor α) is a complex event that involves a variety of mediators and regulators, including proteases, the sphingolipid ceramide and Bcl-2 family members. It is now well...