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1-21 of 21
Keywords: tumour necrosis factor α (TNFα)
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Articles
Chitinase-3-like protein 1 protects skeletal muscle from TNFα-induced inflammation and insulin resistance
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2014) 459 (3): 479–488.
Published: 11 April 2014
... PAR2. Hence, we suggest CHI3L1 to be an autoprotective factor that is activated to protect skeletal muscle from the negative effect of TNFα. chitinase-3-like protein 1 (CHI3L1) inflammation myokine skeletal muscle cell tumour necrosis factor α (TNFα) 28 8 2013 6 2 2014 11...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2013) 449 (1): 275–284.
Published: 07 December 2012
... ]; RelA, GCUGAUGUGCACCGACAAG [ 13 ]; TfR1_A, CCAAUACAGAGCAGACAUA; TfR1_B, ACUUGCUGUAGAUGAAGAA; TfR1_C, CUUCCAGACUAACAACAGA; and IKKγ, ACAGGAGGUGAUCGAUAAG [ 14 ]. inhibitor of nuclear factor κB kinase (IKK) iron nuclear factor κB (NF-κB) transferrin transferrin receptor 1 (TfR1) tumour necrosis...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2012) 443 (3): 857–867.
Published: 16 April 2012
...://creativecommons.org/licenses/by-nc/2.5/ ) which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited. bioinformatics cytokine inflammation promoter PIK3CD tumour necrosis factor α (TNFα) Antibodies were as follows: anti...
Includes: Supplementary data
Articles
Induction of group IVC phospholipase A 2 in allergic asthma: transcriptional regulation by TNFα in bronchoepithelial cells
Available to PurchaseJustin S. Bickford, Kimberly J. Newsom, John-David Herlihy, Christian Mueller, Benjamin Keeler, Xiaolei Qiu, Jewell N. Walters, Nan Su, Shannon M. Wallet, Terence R. Flotte, Harry S. Nick
Journal:
Biochemical Journal
Biochem J (2012) 442 (1): 127–137.
Published: 27 January 2012
... phospholipase A 2 (PLA2G4C) inflammation lung tumour necrosis factor α (TNFα) The initial physiological response to infection or tissue injury is inflammation. A defining event in this response is the liberation of bioactive lipid metabolites of AA (arachidonic acid), the eicosanoids...
Includes: Supplementary data
Articles
Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2012) 441 (1): 339–346.
Published: 14 December 2011
...)-associated nuclear factor κB activator]-binding kinase 1 (TBK1) tumour necrosis factor α (TNFα) Toll-like receptor (TLR) Pellino was originally discovered in the Toll signalling pathway of Drosophila melanogaster as a protein that interacts with Pelle, the orthogue of IRAK {IL-1R [IL (interleukin...
Includes: Supplementary data
Articles
Phosphorylation of cAMP-specific PDE4A5 (phosphodiesterase-4A5) by MK2 (MAPKAPK2) attenuates its activation through protein kinase A phosphorylation
Available to PurchaseKirsty F. MacKenzie, Derek A. Wallace, Elaine V. Hill, Diana F. Anthony, David J. P. Henderson, Daniel M. Houslay, J. Simon C. Arthur, George S. Baillie, Miles D. Houslay
Journal:
Biochemical Journal
Biochem J (2011) 435 (3): 755–769.
Published: 13 April 2011
... XAP2) cAMP-specific phosphodiesterase-4 (PDE4) disrupted in schizophrenia 1 (DISC1) mitogen-activated protein kinase-activated protein kinase 2 (MK2 also called MAPKAPK2) protein kinase A (PKA) tumour necrosis factor α (TNFα) MAPKs (mitogen-activated protein kinases) provide...
Articles
p65 controls NF-κB activity by regulating cellular localization of IκBβ
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2011) 434 (2): 253–263.
Published: 11 February 2011
... gene expression inhibitory κB β (IκBβ) nuclear factor κB (NF-κB) tumour necrosis factor α (TNFα) NF-κB (nuclear factor κB) is a homo- or hetero-dimeric inducible transcription factor composed of several mammalian Rel proteins: p65 (RelA), p50 (NFKB1), p52 (NFKB2), c-Rel and RelB [ 1...
Includes: Supplementary data
Articles
Induced, selective proteolysis of MLK3 negatively regulates MLK3/JNK signalling
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2010) 427 (3): 435–443.
Published: 14 April 2010
... mitogen-activated protein kinase (MAPK) mixed lineage kinase 3 (MLK3) proteasome tumour necrosis factor α (TNFα) The activities and signalling pathways of many protein kinases are controlled through post-translational modifications. Reversible phosphorylation is the most common post...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2010) 426 (3): 345–354.
Published: 24 February 2010
... (CXCL2)/macrophage inflammatory protein 2 (MIP2) histone acetylation histone deacetylase 1 (HDAC1) nuclear factor κB (NF-κB) RelA (p65) tumour necrosis factor α (TNFα) 1 To whom correspondence should be addressed (email [email protected] ). Primers used were: Cxcl1 (FWD...
Includes: Supplementary data
Articles
G-protein-coupled-receptor kinases mediate TNFα-induced NF-κB signalling via direct interaction with and phosphorylation of IκBα
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2010) 425 (1): 169–180.
Published: 14 December 2009
... should be addressed (email [email protected] ). 18 6 2009 18 9 2009 2 10 2009 2 10 2009 © The Authors Journal compilation © 2010 Biochemical Society 2010 G-protein-coupled-receptor kinase (GRK) inflammation macrophage nuclear factor κB (NF-κB) tumour necrosis factor...
Includes: Supplementary data
Articles
Post-transcriptional regulation of CLMP mRNA is controlled by tristetraprolin in response to TNFα via c-Jun N-terminal kinase signalling
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2008) 410 (3): 575–583.
Published: 27 February 2008
... 30 11 2007 © The Authors Journal compilation © 2008 Biochemical Society 2008 blood–testis barrier coxsackie- and adenovirus-receptor-like membrane protein (CLMP) post-transcriptional regulation Sertoli cell tight junction tumour necrosis factor α (TNFα...
Articles
Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex
Available to PurchaseHeidi Mendoza, David G. Campbell, Kerry Burness, James Hastie, Natalia Ronkina, Jae-Hyuck Shim, J. Simon C. Arthur, Roger J. Davis, Matthias Gaestel, Gary L. Johnson, Sankar Ghosh, Philip Cohen
Journal:
Biochemical Journal
Biochem J (2008) 409 (3): 711–722.
Published: 15 January 2008
... kinase 1 (TAK1) tumour necrosis factor α (TNFα) The uncontrolled production of TNFα (tumour necrosis factor α) and other pro-inflammatory cytokines is a major cause of chronic inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease. TAK1 (transforming growth factor-β...
Articles
Identification of a responsible promoter region and a key transcription factor, CCAAT/enhancer-binding protein ϵ, for up-regulation of PHGPx in HL60 cells stimulated with TNFα
Available to PurchaseHiroyuki Hattori, Hirotaka Imai, Nozomu Kirai, Kazuhisa Furuhama, Osamu Sato, Kumiko Konishi, Yasuhito Nakagawa
Journal:
Biochemical Journal
Biochem J (2007) 408 (2): 277–286.
Published: 14 November 2007
... 2 2007 8 8 2007 10 8 2007 10 8 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 CCAAT/enhancer-binding protein (C/EBP) HL60 cell phospholipid hydroperoxide glutathione peroxidase (PHGPx) promoter activity tumour necrosis factor α (TNFα...
Articles
Basic helix–loop–helix protein E47-mediated p21Waf1/Cip1 gene expression regulates apoptosis of intestinal epithelial cells
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2007) 407 (2): 243–254.
Published: 25 September 2007
... should be addressed (email [email protected] ). 28 2 2007 25 6 2007 9 7 2007 9 7 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 α-difluromethylornithine (DFMO) epithelium p130Cas polyamine Src tumour necrosis factor α (TNFα...
Articles
Inhibition of hepatocyte nuclear factor 4 transcriptional activity by the nuclear factor κB pathway
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2006) 398 (3): 439–450.
Published: 29 August 2006
... hepatocyte nuclear factor 4 (HNF-4) nuclear factor κB (NF-κB) transcriptional inhibition tumour necrosis factor α (TNFα) HNF-4 (hepatocyte nuclear factor 4) belongs to the hormone nuclear receptor gene superfamily of transcription factors on the basis of its domain architecture, which...
Articles
Tumour necrosis factor α causes hypoferraemia and reduced intestinal iron absorption in mice
Available to PurchaseAbas H. Laftah, Naveen Sharma, Matthew J. Brookes, Andrew T. McKie, Robert J. Simpson, Tariq H. Iqbal, Chris Tselepis
Journal:
Biochemical Journal
Biochem J (2006) 397 (1): 61–67.
Published: 14 June 2006
... in 62.5 mM Tris/HCl, pH 6.8, for 30 min at 70 °C. 6 2 2006 24 3 2006 27 3 2006 27 3 2006 The Biochemical Society, London 2006 anaemia of chronic disease (ACD) ferritin hypoferraemia iron iron-regulated protein 1 (IREG1) tumour necrosis factor α (TNFα...
Articles
Sphingomyelins suppress the targeted disruption of lysosomes/endosomes by the photosensitizer NPe6 during photodynamic therapy
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2005) 392 (2): 325–334.
Published: 22 November 2005
.... apoptosis cathepsin D lysosome NPe6 3- O -methylsphingomyelin photodynamic therapy procaspase tumour necrosis factor α (TNFα) The reagents and procedures used for the preparation and processing of cell lysates, SDS gel electrophoresis and immunodetection of caspase 3 have been described...
Articles
Lipopolysaccharide rapidly modifies adenosine receptor transcripts in murine and human macrophages: role of NF-κB in A 2A adenosine receptor induction
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2005) 391 (3): 575–580.
Published: 25 October 2005
....). adenosine receptor ATL146e inflammation lipopolysaccharide macrophage tumour necrosis factor α (TNFα) Adenosine released from stressed cells can act as a physiological inhibitor of inflammation [ 1 ]. Utilization of ATP during periods of high metabolic activity leads to an increased...
Articles
Tumour necrosis factor α induces co-ordinated activation of rat GSH synthetic enzymes via nuclear factor κB and activator protein-1
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2005) 391 (2): 399–408.
Published: 10 October 2005
... To whom correspondence should be addressed (email [email protected] ). 12 5 2005 4 7 2005 13 7 2005 13 7 2005 The Biochemical Society, London 2005 activator protein 1 (AP-1) glutamate–cysteine ligase (GCL) GSH synthetase (GSS) nuclear factor κB (NF-κB) tumour necrosis...
Articles
Activation of RelA homodimers by tumour necrosis factor α: a possible transcriptional activator in human vascular endothelial cells
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2005) 390 (1): 317–324.
Published: 09 August 2005
... factor-κB1 (NF-κB1) RelA homodimer tumour necrosis factor α (TNFα) In a variety of cell types, cytokines regulate the expression of many viral and cellular genes through the transcriptional factor NF-κB (nuclear factor κB) (reviewed in [ 1 – 3 ]). NF-κB was first described as a heterodimer...
Articles
A mitochondrial pool of sphingomyelin is involved in TNFα-induced Bax translocation to mitochondria
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2005) 386 (3): 445–451.
Published: 08 March 2005
[email protected] ). 22 9 2004 27 10 2004 29 10 2004 29 10 2004 The Biochemical Society, London 2005 apoptosis Bax translocation ceramide mitochondrion sphingomyelinase tumour necrosis factor α (TNFα) Several studies have demonstrated strong links between ceramide...