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1-7 of 7
Keywords: uncoupling
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Articles
Journal:
Biochemical Journal
Biochem J (2016) 473 (22): 4103–4127.
Published: 10 November 2016
... and the endosymbiont (mitochondrion) allowed larger varieties of substrates (with different F/N ratios) to be oxidized, but high F/N ratios increase ROS formation. This might have led to carnitine shuttles, uncoupling proteins, and multiple antioxidant mechanisms, especially linked to fatty acid oxidation [BioEssays...
Includes: Supplementary data
Articles
Luis A. Luévano-Martínez, Carlos Barba-Ostria, Daniela Araiza-Olivera, Natalia Chiquete-Félix, Sergio Guerrero-Castillo, Eduardo Rial, Dimitris Georgellis, Salvador Uribe-Carvajal
Journal:
Biochemical Journal
Biochem J (2012) 443 (1): 317–325.
Published: 14 March 2012
... (uncoupling protein). Significantly, we identified two amino acid changes at the matrix gate of Yl Oac and Sc Oac, tyrosine to phenylalanine and methionine to leucine. We studied the role of these amino acids by expressing both wild-type and specifically mutated Oacs in an Oac-null S. cerevisiae strain...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2011) 437 (1): 135–140.
Published: 14 June 2011
... activity when ATP was used as the substrate. However, GTP, which bound poorly to the ϵ subunit, did not support efficient H + pumping. Addition of small amounts of ATP to the GTP substrate restored coupling between GTPase and H + pumping activities. Similar uncoupling was observed when TF o F 1 contained...
Articles
Journal:
Biochemical Journal
Biochem J (2007) 407 (1): 129–140.
Published: 12 September 2007
...Phing-How Lou; Birgit S. Hansen; Preben H. Olsen; Søren Tullin; Michael P. Murphy; Martin D. Brand We have discovered that some weak uncouplers (typified by butylated hydroxytoluene) have a dynamic range of more than 10 6 in vitro : the concentration giving measurable uncoupling is less than one...
Articles
Journal:
Biochemical Journal
Biochem J (2000) 351 (3): 805–810.
Published: 24 October 2000
...Michail TONKONOGI; Anna KROOK; Brandon WALSH; Kent SAHLIN Uncoupled respiration (UCR) is an essential property of muscle mitochondria and has several functions in the cell. We hypothesized that endurance training may alter the magnitude and properties of UCR in human muscle. Isolated mitochondria...
Articles
Susana CADENAS, Julie A. BUCKINGHAM, Julie ST-PIERRE, Keith DICKINSON, Robert B. JONES, Martin D. BRAND
Journal:
Biochemical Journal
Biochem J (2000) 351 (2): 307–311.
Published: 10 October 2000
... (the frog Rana temporaria ), suggesting that AMP activation is not primarily for thermogenesis. AMP activation in rat muscle mitochondria is unchanged when uncoupling protein-3 is doubled by starvation, indicating that this protein is not involved in the AMP effect. AMP activation is, however, abolished...
Articles
Journal:
Biochemical Journal
Biochem J (2000) 348 (1): 209–213.
Published: 09 May 2000
... to free Mg 2+ concentration but is insensitive to NTPs or NDPs at 1 mM. 13 12 1999 24 2 2000 10 3 2000 The Biochemical Society, London © 2000 2000 ADP ATP GDP proton leak uncoupling Biochem. J. (2000) 348, 209 213 (Printed in Great Britain) 209 Effects of magnesium...