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Keywords: vaccine
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Articles
Getting oriented with antibodies
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2017) 474 (4): 517–519.
Published: 03 February 2017
...Erik H. Klontz; Eric J. Sundberg Neisseria meningitidis is a Gram-negative bacterium capable of causing deadly invasive disease. Two recently developed vaccines against N. meningitidis serogroup B include recombinant factor H binding protein (fHbp), a surface protein that meningococci use to evade...
Articles
Mining the bacterial unknown proteome: identification and characterization of a novel family of highly conserved protective antigens in Staphylococcus aureus
Available to PurchaseChristina Schluepen, Enrico Malito, Ambra Marongiu, Markus Schirle, Elisabeth McWhinnie, Paola Lo Surdo, Marco Biancucci, Fabiana Falugi, Vincenzo Nardi-Dei, Sara Marchi, Maria Rita Fontana, Benedetta Lombardi, Maria Grazia De Falco, C. Daniela Rinaudo, Glen Spraggon, Mikkel Nissum, Fabio Bagnoli, Guido Grandi, Matthew J. Bottomley, Sabrina Liberatori
Journal:
Biochemical Journal
Biochem J (2013) 455 (3): 273–284.
Published: 10 October 2013
... a possible important role for these proteins in S. aureus biology and pathogenesis. These findings identify the Csa family as new potential vaccine candidates, and underline the importance of mining the bacterial unknown proteome to identify new targets for preventive vaccines. The structural co-ordinates...
Includes: Supplementary data
Articles
Structural and functional characterization of the Staphylococcus aureus virulence factor and vaccine candidate FhuD2
Available to PurchasePaolo Mariotti, Enrico Malito, Marco Biancucci, Paola Lo Surdo, Ravi P. N. Mishra, Vincenzo Nardi-Dei, Silvana Savino, Mikkel Nissum, Glen Spraggon, Guido Grandi, Fabio Bagnoli, Matthew J. Bottomley
Journal:
Biochemical Journal
Biochem J (2013) 449 (3): 683–693.
Published: 09 January 2013
.... The development of antibiotic resistance in S. aureus highlights the need for a preventive vaccine. In the present paper we explore the structure and function of FhuD2 (ferric-hydroxamate uptake D2), a staphylococcal surface lipoprotein mediating iron uptake during invasive infection, recently described...
Includes: Supplementary data