... of the intracellular storage pool of GLUT4 is not well understood. Immunofluorescence staining shows that, under basal conditions, the major population of GLUT4 resides in the perinuclear compartment. At the same time, biochemical fractionation reveals that GLUT4 is localized in IRVs (insulin-responsive vesicles...

...Robert M. Hagan; Jane Worner-Gibbs; David C. Wilton Liver FABP (fatty-acid-binding protein) binds a variety of non-polar anionic ligands including fatty acids, fatty acyl CoAs, lysophospholipids and bile acids. Liver FABP is also able to bind to anionic phospholipid vesicles under conditions of low...

... for phosphorylation, and EEA1 plays an important role in vesicle fusion during endocytosis by controlling endosome docking (summarized in [ 5 ]). We identified a WD-repeat propeller and FYVE domain-containing protein, ProF (propeller-FYVE protein), as interaction partner of the serine/threonine kinase Akt. Akt...

... septins has an impact on function by targeting septin macromolecular complexes to specific cellular locations. The Biochemical Society, London 2004 heterotypic septin–septin interaction homotypic septin–septin interaction macromolecular complex septin group vesicle yeast two-hybrid system...

...Penelope BUXTON; Xiang-Ming ZHANG; Bong WALSH; Absorn SRIRATANA; Irina SCHENBERG; Elizabeth MANICKAM; Tony ROWE Members of the SNARE (soluble N -ethylmaleimide-sensitive fusion protein attachment protein receptor) superfamily [syntaxins, VAMPs (vesicle-associated membrane proteins) and SNAP25...