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Keywords: viral hepatitis
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Interferons activate the p42/44 mitogen-activated protein kinase and JAK-STAT (Janus kinase-signal transducer and activator transcription factor) signalling pathways in hepatocytes: differential regulation by acute ethanol via a protein kinase C-dependent mechanism

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Van-Anh T. NGUYEN, Jianping CHEN, Feng HONG, Edward J. N. ISHAC, Bin GAO
Journal: Biochemical Journal
Biochem J (2000) 349 (2): 427–434.
https://doi.org/10.1042/bj3490427
Published: 10 July 2000
...Van-Anh T. NGUYEN; Jianping CHEN; Feng HONG; Edward J. N. ISHAC; Bin GAO Interferons (IFNs) have been used in the treatment of viral hepatitis. However, their effectiveness is much reduced (< 10%) in alcoholics. The mechanism underlying this resistance remains unknown. Here, we report that IFN-α...
View articletitled, Interferons activate the p42/44 mitogen-activated protein kinase and JAK-STAT (Janus kinase-signal transducer and activator transcription factor) signalling pathways in hepatocytes: differential regulation by acute ethanol via a protein kinase C-dependent mechanism
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