..., ARGKKECKDDRCRLLMKRGSFSYV) belonging to the cathelicidin family was identified from the skin of the plateau frog Nanorana ventripunctata . Cathelicidin-NV showed strong wound healing-promoting activity in a murine model with a full-thickness dermal wound. It directly enhanced the proliferation of keratinocyte cells...

... [email protected] ). 10 4 2008 11 9 2008 26 9 2008 26 9 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 apolipoprotein A endothelial cell kinase phosphorylation integrin αVβ3 transforming growth factor-β wound healing Elevated plasma...

... of fibroblast proliferation by TGF-β1 is critical to tissue damage and remodelling processes. During wound healing, TGF-β1 showed none or low expression at an early stage, and kept increasing until 100–1000-fold elevation at later stages [ 10 – 12 ]. Thus there was increased cell proliferation and chemotactic...

... expressed in cultured human skin fibroblasts, which under normal wound healing processes migrate from surrounding tissues to close the wound. EGF (epidermal growth factor), which induced fibroblast migration, also induced AQP3 expression in a time- and dose-dependent manner. CuSO 4 and NiCl 2 , previously...

... glycosylation suprabasal keratinocytes uPA uPAR domain family wound healing Abbreviations used: Caps, 3-(cyclohexylamino)propane-1-sulphonic acid; C4.4A´, truncated fragment of C4.4A; GPI, glycosyl-phosphatidylinositol; hAG, human anterior gradient; Ly-6, leucocyte antigen 6; MALDI–TOF-MS, matrix...

... is a fundamental aspect in numerous normal and pathological processes, including embryonic development, wound healing, inflammation and metastasis of tumour cells [1,2]. Various factors such as growth factors and extracellular matrix (ECM) proteins in the cellular microenvironment par- ticipate in the regulation...

... mechanically stimulated by scratching, and the cells were forced to migrate in a given direction. In this wound-healing assay, the AA-MRLC-expressing cells migrated much more slowly than the wild-type MRLC-expressing cells. In the case of DD-MRLC- and AD-MRLC-expressing cells, no significant differences...

... to activate latent TGF-β1. Any TSP-mediated activation of TGF-β1 must depend on additional factor(s) not present in our systems. cytokine fibroblast platelet wound healing Biochem. J. (2000) 350, 291 298 (Printed in Great Britain) 291 Thrombospondin 1 does not activate transforming growth factor b1...

... site may strengthen this interaction. 1 To whom correspondence should be addressed (e-mail [email protected] ). 13 5 1998 2 11 1998 8 12 1998 The Biochemical Society, London © 1999 1999 dissociation constant ELISA fibrin clot thrombus wound healing...