Plastic microfluidic array platforms and synergistic multiplexed assay chemistries are under development for a variety of applications, including assays of gene expression, proteomics, genotyping, DNA sequencing and fragment analysis, sample prepraration and high-throughput pharmaceutical discovery. The low production costs of plastic substrates makes possible economical single-use device arrays, eliminating cleaning and sample-to-sample carryover contamination. Hundreds of microchannels and reservoirs are readily included on a single microtitre-plate-size substrate, enabling the manufacture of highly parallel fluidic array systems to increase throughput and speed.
Application of disposable plastic microfluidic device arrays with customized chemistries to multiplexed biochemical assays
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A. J. Ricco, T. D. Boone, Z. H. Fan, I. Gibbons, T. Matray, S. Singh, H. Tan, T. Tian, S. J. Williams; Application of disposable plastic microfluidic device arrays with customized chemistries to multiplexed biochemical assays. Biochem Soc Trans 1 April 2002; 30 (2): 73–78. doi: https://doi.org/10.1042/bst0300073
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