Corticotropin-releasing hormone (CRH) and related peptides (urocortins, sauvagine, urotensin) play a central role in the co-ordination of autonomic, behavioural, cardiovascular, immune and endocrine responses to stressful stimuli. Their actions are mediated through activation of two types of G-protein-coupled receptors encoded by separate genes. In this review we focus on the diverse structural and functional characteristics of the family of CRH-like peptides and their receptors.
Conference Article| August 01 2002
Corticotropin-releasing hormone receptors
E. W. Hillhouse;
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E. W. Hillhouse, H. Randeva, G. Ladds, D. Grammatopoulos; Corticotropin-releasing hormone receptors. Biochem Soc Trans 1 August 2002; 30 (4): 428–432. doi: https://doi.org/10.1042/bst0300428
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