The synthesis and the insertion of the metallo-centre of NiFe-hydrogenases is a complex process, in which seven maturation enzymes plus ATP, GTP and carbamoyl phosphate are involved. The review summarizes what is known about the properties and activities of these auxiliary proteins, and postulates a pathway along which maturation may take place.
Conference Article| August 01 2002
Metal insertion into NiFe-hydrogenases
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M. Blokesch, A. Paschos, E. Theodoratou, A. Bauer, M. Hube, S. Huth, A. Böck; Metal insertion into NiFe-hydrogenases. Biochem Soc Trans 1 August 2002; 30 (4): 674–680. doi: https://doi.org/10.1042/bst0300674
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