The pathogenic Neisseria have a siderophore-independent iron-uptake system reliant on a direct interaction between the bacterial cell and transferrin. In the meningococcus this uptake system is dependent on two surface-exposed transferrin-binding proteins. This short account will review our current knowledge of the transferrin-mediated iron-acquisition system of pathogenic Neisseria.
Conference Article| August 01 2002
Transferrin-mediated iron acquisition by pathogenic Neisseria
R. W. Evans;
R. W. Evans 1
1Metalloprotein Research Group, The Randall Centre for Molecular Mechanisms of Cell Function, King's College London, 3.6A New Hunt's House, Guy's Campus, London SE1 1UL, U.K.
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R. W. Evans, J. S. Oakhill; Transferrin-mediated iron acquisition by pathogenic Neisseria. Biochem Soc Trans 1 August 2002; 30 (4): 705–707. doi: https://doi.org/10.1042/bst0300705
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