The Drosophila Toll receptor controls the immune response to Gram-positive bacteria and fungi by activating a signalling pathway partially conserved throughout evolution. The Drosophila genome encodes eight additional Toll-related receptors, most of which appear to carry out developmental rather than immune functions. One exception may be Toll-9, which shares structural and functional similarities with mammalian TLRs.
Conference Article| June 01 2003
Toll and Toll-like receptors in Drosophila
Biochem Soc Trans (2003) 31 (3): 648-651.
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H. Bilak, S. Tauszig-Delamasure, J.-L. Imler; Toll and Toll-like receptors in Drosophila. Biochem Soc Trans 1 June 2003; 31 (3): 648–651. doi: https://doi.org/10.1042/bst0310648
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