In this work we present a probabilistic model to estimate summaries of Affymetrix GeneChip probe level data. Comparisons with two different models were made both on a publicly available dataset and on a study performed in our laboratory, showing that our model performs better for consistency of fold change.
A probabilistic model for the extraction of expression levels from oligonucleotide arrays
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M. Milo, A. Fazeli, M. Niranjan, N.D. Lawrence; A probabilistic model for the extraction of expression levels from oligonucleotide arrays. Biochem Soc Trans 1 December 2003; 31 (6): 1510–1512. doi: https://doi.org/10.1042/bst0311510
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