The serum- and glucocorticoid-inducible kinase SGK1 is an ubiquitously expressed kinase with the ability to regulate a variety of transport systems. Recent observations point to a role of SGK1 in the regulation of diverse physiological functions such as epithelial transport and cardiac and neuronal excitability. At least partially through its effect on transport, SGK1 contributes to a number of pathophysiological conditions including metabolic syndrome and fibrosing disease.
Conference Article| February 01 2005
Transport regulation by the serum- and glucocorticoid-inducible kinase SGK1
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F. Lang, V. Vallon, F. Grahammer, M. Palmada, C. Böhmer; Transport regulation by the serum- and glucocorticoid-inducible kinase SGK1. Biochem Soc Trans 1 February 2005; 33 (1): 213–215. doi: https://doi.org/10.1042/BST0330213
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