The production of dihydrogen by Escherichia coli and other members of the Enterobacteriaceae is one of the classic features of mixed-acid fermentation. Synthesis of the multicomponent, membrane-associated FHL (formate hydrogenlyase) enzyme complex, which disproportionates formate into CO2 and H2, has an absolute requirement for formate. Formate, therefore, represents a signature molecule in the fermenting E. coli cell and factors that determine formate metabolism control FHL synthesis and consequently dihydrogen evolution.
Conference Article| February 01 2005
Formate and its role in hydrogen production in Escherichia coli
- Views Icon Views
- Share Icon Share
- Cite Icon Cite
R.G. Sawers; Formate and its role in hydrogen production in Escherichia coli. Biochem Soc Trans 1 February 2005; 33 (1): 42–46. doi: https://doi.org/10.1042/BST0330042
Download citation file: