Systems biology describes the collection of a set of measurements on a system, integrated with a mathematical model of that system. The model and the measurements must be made together and refined iteratively, requiring close collaboration between biologists and modellers. A complete cell is probably too large and complicated to model yet, but simplified subsystems will probably produce valuable results. I consider various ways of simplifying the system and conclude that the biggest challenge is to get everyone working together productively.
Conference Article| June 01 2005
Systems biology: will it work?
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M.P. Williamson; Systems biology: will it work?. Biochem Soc Trans 1 June 2005; 33 (3): 503–506. doi: https://doi.org/10.1042/BST0330503
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