An optical technique, dual-polarization interferometry, has been used to examine lipid structures at the solid/liquid interface. Changes in the lipid structures, in real time, were examined as a consequence of challenging them with a peptide (melittin) that is known to induce liposome rupture. This work suggests that it should be possible to obtain a better understanding of the detail of the melittin rupture process.
Quantification of the effects of melittin on liposome structure
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J. Popplewell, N. Freeman, S. Carrington, G. Ronan, C. McDonnell, R.C. Ford; Quantification of the effects of melittin on liposome structure. Biochem Soc Trans 26 October 2005; 33 (5): 931–933. doi: https://doi.org/10.1042/BST0330931
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