The African trypanosome Trypanosoma brucei has a precarious existence as an extracellular parasite of the mammalian bloodstream, where it is faced with continuous immune attack. Key to survival is a dense VSG (variant surface glycoprotein) coat, which is repeatedly switched during the course of a chronic infection. New data demonstrate a link between VSG synthesis and cell cycle progression, indicating that VSG is monitored during the trypanosome cell cycle.
Conference Article| October 26 2005
Maintaining the protective variant surface glycoprotein coat of African trypanosomes
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G. Rudenko; Maintaining the protective variant surface glycoprotein coat of African trypanosomes. Biochem Soc Trans 26 October 2005; 33 (5): 981–982. doi: https://doi.org/10.1042/BST0330981
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