Dystroglycan, a ubiquitous membrane-spanning cell adhesion molecule, is a crucial link between the actin cytoskeleton and the extracellular matrix. With a wide expression pattern and multiple interacting proteins, not only is dystroglycan now thought to be important as a structural molecule but also new research has suggested that it has a role in cell signalling, cytoskeleton reorganization and as a potential tumour suppressor.
Conference Article| October 26 2005
Dystroglycan: a multifunctional adaptor protein
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J.R. Higginson, S.J. Winder; Dystroglycan: a multifunctional adaptor protein. Biochem Soc Trans 26 October 2005; 33 (6): 1254–1255. doi: https://doi.org/10.1042/BST0331254
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