The cytoskeletal protein talin plays a key role in coupling the integrin family of cell adhesion molecules to the actin cytoskeleton. In this paper I present a brief review on talin and summarize our recent studies, in which we have taken both genetic and structural approaches to further elucidate the function of the protein.
Conference Article| October 26 2005
Genetic, biochemical and structural approaches to talin function
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D.R. Critchley; Genetic, biochemical and structural approaches to talin function. Biochem Soc Trans 26 October 2005; 33 (6): 1308–1312. doi: https://doi.org/10.1042/BST0331308
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