PTH (parathyroid hormone), acting via type 1 PTH receptors, is a major regulator of plasma [Ca2+]. The G-protein, Gs, is an essential component of the sequence linking PTH to plasma Ca2+ regulation, but the relative importance of intracellular signals, including Ca2+ and cAMP, that lie downstream of Gs is not resolved.

Keywords:
calcium, cAMP, G-protein, inositol 1,4,5-trisphosphate, intracellular signalling, parathyroid hormone
© 2006 The Biochemical Society
2006
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