Kainate receptors are composed of several subunits and splice variants, but the relevance of this diversity is still not well understood. The subunits and splice variants show great divergence in their C-terminal cytoplasmic tail region, which has been identified as a region of interaction with a number of protein partners. Differential trafficking of kainate receptors to neuronal compartments is likely to rely on interactions with distinct subsets of protein partners. This review summarizes our knowledge of the regulation of trafficking of kainate receptors and focuses on the identification and characterization of functions of interacting partners.
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Conference Article| October 25 2006
Kainate receptor-interacting proteins and membrane trafficking
F. Coussen ;
C. Mulle 1
1CNRS UMR 5091, Laboratoire ‘Physiologie Cellulaire de la Synapse’, Bordeaux Neuroscience Institute, University of Bordeaux, 33077 Bordeaux Cedex, France
1To whom correspondence should be addressed (email email@example.com).
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F. Coussen, C. Mulle; Kainate receptor-interacting proteins and membrane trafficking. Biochem Soc Trans 1 October 2006; 34 (5): 927–930. doi: https://doi.org/10.1042/BST0340927
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