Although it is now well established that PI3K (phosphoinositide 3-kinase) is a key enzyme in several intracellular processes, there are still relatively few reports that precisely identify the specific isoforms of PI3K actually involved in such events. The lack of specific inhibitors has made it particularly difficult to address the physiological roles of some isoforms, such as the members of class II. As a consequence, there is still relatively little understanding of the role of these enzymes and the question about the intracellular role of these isoforms still waits for more answers.
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Conference Article| March 20 2007
Role of class II phosphoinositide 3-kinase in cell signalling
M. Falasca 1
1Centre for Cardiovascular Biology and Medicine, Division of Medicine, University College London, Rayne Building, 5 University Street, London WC1E 6JJ, U.K.
1To whom correspondence should be addressed (email firstname.lastname@example.org).
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M. Falasca, T. Maffucci; Role of class II phosphoinositide 3-kinase in cell signalling. Biochem Soc Trans 1 April 2007; 35 (2): 211–214. doi: https://doi.org/10.1042/BST0350211
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