Accumulating data suggest that dietary phytochemicals have the potential to moderate deregulated signalling or reinstate checkpoint pathways and apoptosis in damaged cells, while having minimal impact on healthy cells. These are ideal characteristics for chemopreventive and combination anticancer strategies, warranting substantial research effort into harnessing the biological activities of these agents in disease prevention and treatment. However, this requires further investigation into their mode of action and novel approaches to the development of reliable biomarkers.
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Conference Article| October 25 2007
Determining the efficacy of dietary phytochemicals in cancer prevention
M.M. Manson 1
1Cancer Biomarkers and Prevention Group, Department of Cancer Studies and Molecular Medicine, Biocentre, University of Leicester, Leicester LE1 7RH, U.K.
1To whom correspondence should be addressed (email email@example.com).
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M.M. Manson, B.E. Foreman, L.M. Howells, E.P. Moiseeva; Determining the efficacy of dietary phytochemicals in cancer prevention. Biochem Soc Trans 1 November 2007; 35 (5): 1358–1363. doi: https://doi.org/10.1042/BST0351358
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