The NF-κB (nuclear factor κB) transcription factors control cell survival, proliferation and innate and adaptive immune response. Post-translational modifications of key components of the NF-κB pathway provide the molecular basis for signal transmission from the cell membrane to the nucleus. Here, we describe the involvement of different types of ubiquitin modification in the regulation of the NF-κB signalling pathway.
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Conference Article| October 25 2007
Ubiquitin signals in the NF-κB pathway
I. Dikic 1
†Institute of Biochemistry II, Goethe University School of Medicine, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany
‡Mediterranean Institute for Life Sciences, 21000 Split, Croatia
1To whom correspondence should be addressed (email firstname.lastname@example.org).
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J. Terzic, I. Marinovic-Terzic, F. Ikeda, I. Dikic; Ubiquitin signals in the NF-κB pathway. Biochem Soc Trans 1 November 2007; 35 (5): 942–945. doi: https://doi.org/10.1042/BST0350942
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