AAAs (ATPases associated with various cellular activities) form a large group of P-loop NTPases, themselves the most abundant class of protein in all organisms. Because of their importance, since 1995, there has been a biennial meeting focusing on AAAs. The Seventh International Meeting on AAA Proteins was held on 9–13 September 2007 in Cirencester, U.K. and brought together various prominent and promising researchers in the field. The talks that are discussed herein and the corresponding papers that follow this introduction give a good overview of the current areas of research into these proteins.

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