Recent studies of some proteins involved in the formation of focal adhesions are described. These include fibronectin, integrins, talin, Dok1 and filamin. Emphasis is placed on features that facilitate regulated assembly of complexes; these include a modular construction and flexible regions that provide interaction sites whose affinity can be adjusted by conformational masking and phosphorylation.
Conference Article| March 20 2008
Studies of focal adhesion assembly
- Views Icon Views
- Share Icon Share
- Cite Icon Cite
Iain D. Campbell; Studies of focal adhesion assembly. Biochem Soc Trans 1 April 2008; 36 (2): 263–266. doi: https://doi.org/10.1042/BST0360263
Download citation file: