Defective insulin secretion is a hallmark of all forms of diabetes. Whereas Type 1 diabetes has long been known to result from the immune-mediated destruction of β-cells, Type 2 diabetes appears to involve both loss of β-cell mass and glucose sensitivity in the face of extrapancreatic insulin resistance. We summarize here the proceedings of a Biochemical Society Focused Meeting, held at the St Thomas campus of King's College London in December 2007, which highlighted recent research advances targeting the β-cell.
Conference Article| May 21 2008
The pancreatic β-cell: birth, life and death
Guy A. Rutter;
Guy A. Rutter 1
*Department of Cell Biology, Division of Medicine, Faculty of Medicine, Sir Alexander Fleming Building, Imperial College London, Exhibition Road, London SW7 2AZ, U.K.
1To whom correspondence should be addressed (email firstname.lastname@example.org).
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Guy A. Rutter, F. Susan Wong; The pancreatic β-cell: birth, life and death. Biochem Soc Trans 1 June 2008; 36 (3): 267–271. doi: https://doi.org/10.1042/BST0360267
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