In mammalian cells, completion of cytokinesis relies on targeted delivery of recycling membranes to the midbody. At this step of mitosis, recycling endosomes are organized as clusters located at the mitotic spindle poles as well as at both sides of the midbody. However, the mechanism that controls endosome positioning during cytokinesis is not known. Here, we discuss the possible mechanisms that drive the formation of endosomal clusters and the importance of this process for the targeted delivery of recycling membranes to the midbody.
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Conference Article| May 21 2008
Endosome positioning during cytokinesis
Guillaume Montagnac 1
*Institut Curie, Centre de Recherche, Paris F-75248 France
†CNRS, UMR144, Membrane and cytoskeleton dynamics, 26 rue d'Ulm, 75248 Paris Cedex 05, France
1To whom correspondence should be addressed (email email@example.com).
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Guillaume Montagnac, Philippe Chavrier; Endosome positioning during cytokinesis. Biochem Soc Trans 1 June 2008; 36 (3): 442–443. doi: https://doi.org/10.1042/BST0360442
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