miRNAs (microRNAs) are recently discovered regulators of gene expression. They target mRNAs that contain partially complementary sites to the miRNA. The level of complementarity is different between target site–miRNA pairs, and finding target genes has proved to be a bigger challenge than expected. The present paper reviews the different approaches to predict and experimentally identify genes targeted by miRNAs.
Conference Article| November 19 2008
Identification of genes targeted by microRNAs
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Tamas Dalmay; Identification of genes targeted by microRNAs. Biochem Soc Trans 1 December 2008; 36 (6): 1194–1196. doi: https://doi.org/10.1042/BST0361194
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