The ‘new view’ of proteins sees protein reactions as parallel processes occurring along funnelled energy landscapes. These landscapes are generally not smooth, but are superimposed by hills and valleys of different heights and widths leading to roughness on the energy surface. In the present paper, we describe the origins of protein energy landscape roughness, measurements of its scale and its implications.
Conference Article| November 19 2008
Protein energy landscape roughness
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Ruti Kapon, Reinat Nevo, Ziv Reich; Protein energy landscape roughness. Biochem Soc Trans 1 December 2008; 36 (6): 1404–1408. doi: https://doi.org/10.1042/BST0361404
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