Steroid hormones control many aspects of animal physiology and behaviour. They are highly regulated, among other mechanisms, by post-translational modifications of the transcription factors involved in their synthesis and response. In the present review, we will focus on the influence of SUMO (small ubiquitin-related modifier) and ubiquitin modifications on the function of transcription factors involved in adrenal cortex formation, steroidogenesis and the hormonal response.
SUMO and ubiquitin modifications during steroid hormone synthesis and function
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Ana Talamillo, David Martín, Roland Hjerpe, Jonatan Sánchez, Rosa Barrio; SUMO and ubiquitin modifications during steroid hormone synthesis and function. Biochem Soc Trans 1 February 2010; 38 (1): 54–59. doi: https://doi.org/10.1042/BST0380054
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