The mineral-respiring bacterium Shewanella oneidensis uses a protein complex, MtrCAB, composed of two decahaem cytochromes brought together inside a transmembrane porin to transport electrons across the outer membrane to a variety of mineral-based electron acceptors. A proteoliposome system has been developed that contains Methyl Viologen as an internalized electron carrier and valinomycin as a membrane-associated cation exchanger. These proteoliposomes can be used as a model system to investigate MtrCAB function.
Development of a proteoliposome model to probe transmembrane electron-transfer reactions
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Gaye F. White, Zhi Shi, Liang Shi, Alice C. Dohnalkova, James K. Fredrickson, John M. Zachara, Julea N. Butt, David J. Richardson, Thomas A. Clarke; Development of a proteoliposome model to probe transmembrane electron-transfer reactions. Biochem Soc Trans 1 December 2012; 40 (6): 1257–1260. doi: https://doi.org/10.1042/BST20120116
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