The spindle assembly checkpoint is a conserved mitotic signalling pathway that ensures the equal segregation of chromosomes to daughter cells. Despite intensive work in many model organisms, key features of this safety mechanism remain unexplained. In the present review, I briefly summarize advances made in the last few years, and then focus on unexplored corners of this signalling pathway.
Conference Article| November 20 2013
The spindle assembly checkpoint: progress and persistent puzzles
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Silke Hauf; The spindle assembly checkpoint: progress and persistent puzzles. Biochem Soc Trans 1 December 2013; 41 (6): 1755–1760. doi: https://doi.org/10.1042/BST20130240
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