Chemical intervention tools have been beneficial to many investigations elucidating signalling networks and interactions. The present review summarizes the current status of chemical tools to probe phosphoinositide metabolism and signalling. In particular, phosphoinositide-targeting tools are compared with protein-targeting tools with respect to their unique advantages and possible applications.
Conference Article| September 18 2014
Chemical intervention tools to probe phosphoinositide-dependent signalling
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Rudiger Woscholski; Chemical intervention tools to probe phosphoinositide-dependent signalling. Biochem Soc Trans 1 October 2014; 42 (5): 1343–1348. doi: https://doi.org/10.1042/BST20140186
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