The immunological synapse controls T-lymphocyte function by polarizing effector responses towards the antigen-presenting cell. In this review, I discuss the molecular pathways required for synapse assembly, focusing on the central roles played by lipid second-messenger signalling.
Conference Article| November 17 2014
Lipid-based patterning of the immunological synapse
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Morgan Huse; Lipid-based patterning of the immunological synapse. Biochem Soc Trans 1 December 2014; 42 (6): 1506–1511. doi: https://doi.org/10.1042/BST20140191
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