The present article addresses the possibilities offered by yeasts to study the problem of the evolution of moonlighting proteins. It focuses on data available on hexokinase from Saccharomyces cerevisiae that moonlights in catabolite repression and on galactokinase from Kluyveromyces lactis that moonlights controlling the induction of the GAL genes. Possible experimental approaches to studying the evolution of moonlighting hexose kinases are suggested.
Conference Article| November 17 2014
Evolution of moonlighting proteins: insight from yeasts
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Carlos Gancedo, Carmen-Lisset Flores, Juana M. Gancedo; Evolution of moonlighting proteins: insight from yeasts. Biochem Soc Trans 1 December 2014; 42 (6): 1715–1719. doi: https://doi.org/10.1042/BST20140199
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