Inorganic polyphosphate (polyP) is found in all living organisms. The known polyP functions in eukaryotes range from osmoregulation and virulence in parasitic protozoa to modulating blood coagulation, inflammation, bone mineralization and cellular signalling in mammals. However mechanisms of regulation and even the identity of involved proteins in many cases remain obscure. Most of the insights obtained so far stem from studies in the yeast Saccharomyces cerevisiae. Here, we provide a short overview of the properties and functions of known yeast polyP metabolism enzymes and discuss future directions for polyP research.
Review Article| February 09 2016
Enzymes of yeast polyphosphate metabolism: structure, enzymology and biological roles
- Views Icon Views
- Share Icon Share
- Cite Icon Cite
Rūta Gerasimaitė, Andreas Mayer; Enzymes of yeast polyphosphate metabolism: structure, enzymology and biological roles. Biochem Soc Trans 15 February 2016; 44 (1): 234–239. doi: https://doi.org/10.1042/BST20150213
Download citation file: