Primary cilia are sensory organelles that play a role as signalling hubs. Disruption of primary cilia structure and function is increasingly recognised in a range of cancers, with a growing body of evidence suggesting that ciliary disruption contributes to tumourigenesis. This review considers the role of primary cilia in the pathogenesis of endocrine-related cancers.

Keywords:
breast cancers, cilia, endocrine cancer, ovarian cancer, prostate cancer, Von Hippel–Lindau
Subjects:
Cancer, Endocrinology, Organelles & Localization
© 2016 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society
2016
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