Myocardial Infarction (MI) initiates a series of wound healing events that begins with up-regulation of an inflammatory response and culminates in scar formation. The extracellular matrix (ECM) is intricately involved in all stages from initial break down of existing ECM to synthesis of new ECM to form the scar. This review will summarize our current knowledge on the processes involved in ECM remodeling after MI and identify the gaps that still need to be filled.
Understanding the mechanisms that determine extracellular matrix remodeling in the infarcted myocardium
- Views Icon Views
- Share Icon Share
- Cite Icon Cite
Mavis A.A. Tenkorang, Upendra Chalise, Michael J. Daseke, II, Shelby R. Konfrst, Merry L. Lindsey; Understanding the mechanisms that determine extracellular matrix remodeling in the infarcted myocardium. Biochem Soc Trans BST20190113. doi: https://doi.org/10.1042/BST20190113
Download citation file: