Volume 43 (2015) pp 901–907

1. In the ‘Introduction’ section, the sentence

“These drugs share a common mechanism of action, which is also the case for the previously developed anti-hyperglycaemic drugs, glinides [2].”

should read

“These drugs share a common mechanism of action, which is also the case for the more recently developed anti-hyperglycaemic drugs, glinides [2].”

2. In the legend to Figure 1, the sentence

“The line for data obtained for excised patches is drawn according to equation:”

should read

“The line for data obtained for excised patches is drawn according to the equation below:”

and the sentence

“PO is primary determined by the stability of channel open state; it can be reduced by factors such as channel rundown or increased by channel mutations or via Mg-nt activation of the channel [24,35].”

should read

“PO is primarily determined by the stability of channel open state; it can be reduced by factors such as channel rundown or increased by channel mutations or via Mg-nt activation of the channel [24,35].”

3. In the legend to Figure 3, the sentence

IC is the current in drug free solution obtained by averaging the current before and after application, IC50 is the drug concentration at which the inhibition is half maximal, h is the Hill coefficient, L is a scaling factor reflecting the difference between channel activity in control and MgATP-containing solution (L = 1 in the absence of the nt) and a is the fraction of KATP current remaining at gliclazide concentrations that saturate the high-affinity-binding site on SUR1.”

should read

IC is the current in drug-free solution obtained by averaging the current before and after drug application, IC50 is the drug concentration at which the inhibition is half maximal, h is the Hill coefficient, L is a scaling factor reflecting the difference between channel activity in control and MgATP-containing solution (L = 1 in the absence of the nt) and a is the fraction of KATP current remaining at gliclazide concentrations that saturate the high-affinity-binding site on SUR1.”

4. In the ‘Concluding remarks’ section, the sentence

“Drug-induced stimulation of insulin exocytosis via Epac2 (cAMP-activated guanine-nt exchange factor). It has recently been demonstrated that binding of sulphonylureas to this protein requires cAMP [45].”

should read

“For example, sulphonylurea-induced stimulation of insulin exocytosis via Epac2 (cAMP-activated guanine-nt exchange factor) has recently been demonstrated to be cAMP-dependent since binding of sulphonylureas to this protein requires cAMP [45].”